Infant skin doesn’t even show allergic reactions to allergen testing until three months old, and “not enough testing has been done on adults.” That pretty much sums up vaccine safety and effectiveness standards. Infants, toddlers and the aged show “suboptimal antibody response” needed to immunize against the targeted antigen or pathogen. Nevertheless, they are the most heavily targeted subjects by “public health” agencies. There’s a correlation with developing allergies, but MacPhail’s experts are “blinded by the science”, or lack of.
Our immune cells genetic evolution is the turtle against the hare of industrial alterations of our environment. Dr. Steve Galli believes the immune system’s“backward defense” developed in avoidance to natural toxins, increasing survival and reproduction. Strong reactions to ingesting poisons, ranging from toads to berries, and spitting it out rapidly, while avoiding malarial swamps, snake country and swarming hornets increased survival and descendant odds.
This feeds into the “toxin hypothesis of allergy causation” of Margie Profet, a “brilliant evolutionary biologist and MacArthur grant winner.” She believes allergic reactions are the “body’s method of expelling toxins and carcinogens”, based on lower cases of gliomas in allergy sufferers. A huge leap over an abyss of ignorance.
Mast cells, part of our innate immune system can degrade poisons. Dr. Galli used venom from the mole viper, “an admixture of many toxic substances” that early humans would have been in contact with. He had to smuggle it in from Israel, but in the interests of science, not terrorism.
Mice with and without mast cells, or defective mast cells were injected with various venoms from copperheads, rattlesnakas and Gila Monsters. Those that survived were injected again three weeks later, showing a stronger immune response. They could survive a larger dose, building up tolerance rather than sensitizing.
This supports the hypothesis that “our immune systems evolved to rapidly defend against a variety of toxins- from stings to bites. The drawback is that because our environment has been rapidly changing, those of us with strong immune reactions are left with a host of new problems.” Strong or disrupted? Stigmatism is all in the metaphor.
Dr. Charles Blackley traced grass pollen to his own hay fever in the latter 19th century, searching for the “primary exciting cause.” He found it in a vehicle’s dust cloud that set off a prolonged bout of sneezing, observing that pollen expanded when moist, since all his tests were on varieties of pollen in dust.
His practice was in Manchester, England as it became the industrial capital of Britain and Europe, coal fired power and heat as the foundation. Since allergic diseases had been “largely unknown” until the 1820’s, either the environment or humans had changed. Most rural people were agriculturally involved with repeated exposure to pollen on the farm providing immunity, while displaced peasants in the crowding cities who remained allergy free lacked “the nervous predisposition that came along with education.”
His allergy and asthma patients were fellow physicians or theologians, supporting education as causative, unless there were another factor they had in common, like smallpox inoculation. Instead he focused on pollen counts and concluded that hay fever was clearly a physiological reaction to antigens in the immediate environment. Pollen, not ozone, coal smog or other environmental causes blamed at the time.
Naturally his findings were ignored for decades “due to the dominance of bacteriology and germ theory at the end of the 19th century.” Orthodox doctors blamed “severe bacterial respiratory infections that primed the lungs to be hypersensitive.” This theory would persist until the 20th century, long before oral antibiotics were patented and overprescribed.
Asthma is classed an allergic disease, an immune system disorder of the air passageways of the lungs. It is the most deadly allergy, although peanuts get the press. Possibly because it is associated with poor, urban kids, although it actually casts a far wider web than that. Half a million die every year around the planet. There are more deaths from asthma in low and middle income countries according to the World Health Organization, “likely due to lack of medications to control the condition in severe cases with less access to medical resources”, except for GAVI funded vaccines.
Ultrafine Particulates and Nitrogen Dioxide pollution, from motor vehicles, industry, unflued gas-heaters and gas stove tops are known environmental triggers, although her experts are unwilling to declare them causative. As taboo as inoculations. WHO’s focus is on reducing pollution, which they miraculously achieved with their WEFWTF global lockdown. Clear Skies for a spell, except for solar radiation management.
In the last decades, evidence has mounted that ultrafine particulate pollution in the air, (primarily from burning diesel and wood), ranging from “coarse”, less than 10 microns to fine, even smaller than 2.5 microns, or half the size of a red blood cell, increase rates of asthma, heart attacks and strokes. This is not the smoggy soot of yore, because the horizon can look clean and still set off alarm bells in our immune systems.
Children “exposed to the highest level of air pollution early in their lives, were more likely to develop asthma by age 7”, even if they moved to areas with lower levels. Dr. Patrick Ryan, epidemiologist with the Cincinnati Childhood Allergy and Air Pollution Study, was “still hesitant to say that environment exposure alone- in this case diesel particles in the air- is the true culprit.”
Theoretically other confounding factors like poverty, diet, more cockroach dust and black mold have influence (certainly not vaccines), although he is willing to go out on the professional limb, as “absolutely certain it’s a contributor.” It seems unlikely he will veer “out of his lane” by lobbying for cleaner diesel exhaust, or even fast growing tree shields along highways in urban residential areas.